The mission of ADVANCE is to apply predictive computational modeling, data-driven approaches, and innovations in cardiac imaging to patient care, and specifically, to the diagnosis and treatment of cardiovascular disease. ADVANCE will utilize innovations in clinical imaging, a novel disease-specific personalized computational modeling (Virtual Heart platform), and statistical and machine learning on clinical data to predict the functional behavior of the patient’s heart under a variety of conditions, and to suggest therapeutic approaches for heart rhythm disorders that are optimal for the given patient. This will engender accurate and precise clinical decision-making regarding personalized treatment and optimized cardiac patient care.
Our vision for the future is to transform contemporary cardiac patient care and usher in new personalized approaches to heart health. The blend of medicine with engineering and data-driven approaches will democratize cardiac health care delivery, as a wider range of health care practitioners and centers will be able to perform the decision-making tasks, often with a click of the mouse (or a few). Development of robust, inexpensive, non-invasive diagnostic and prognostic approaches for assessing cardiac dysfunction and for guiding therapies will lead to reduction in health care costs, and to improvement of patient well-being.