A Johns Hopkins team has published landmark results showing that virtual replicas of individual patients’ hearts — so-called “digital twins” — can guide life-saving cardiac procedures with remarkable precision. The findings, reported April 1, 2026 in the New England Journal of Medicine, represent one of the first clinical trials of Read more
We are honored to have Professor Trayanova and our work being featured in Johns Hopkins University’s 2025 Hop Quiz celebrating 150 years of innovation and discovery! We won’t tell you for which question but you will probably guess when you see it. You can watch the video here. Or forward Read more
Researchers in the Trayanova Lab at Johns Hopkins University, led by ADVANCE member Dr. Natalia Trayanova, as well as ADVANCE members from the Johns Hopkins School of Medicine and other collaborators, have developed a new AI tool that significantly improves prediction of sudden cardiac death in patients with hypertrophic cardiomyopathy. Read more
ADVANCE proudly announces that Natalia Trayanova, Murray B. Sachs Professor of Biomedical Engineering and a global leader in computational cardiology, has been elected to the Board of Trustees of the Heart Rhythm Society—the premier professional organization for more than 9,000 specialists in cardiac rhythm disorders across 90 countries. Trayanova, already Read more
Several members of ADVANCE at Johns Hopkins, as well as collaborators at other institutions, have published DIMON (Diffeomorphic Mapping Operator Learning), an AI framework, in Nature Computational Science. This model accelerates the approximation of partial differential equations (PDEs) in complex engineering problems by thousands of times, enabling personal computers to Read more
From the press release: The U.S. National Science Foundation, in collaboration with the National Institutes of Health (NIH) and the Food and Drug Administration (FDA), has awarded over $6 million in research funding across seven projects to explore the development of digital twins, dynamic virtual representations of physical objects or Read more
JHU Selects ADVANCE ECG Deep Learning Project for Discovery Award Johns Hopkins University’s Discovery Awards encourage faculty from various disciplines to collaborate in addressing multifaceted challenges and pushing the boundaries of understanding. In 2024, 44 Discovery Awards were given to interdisciplinary faculty teams, chosen from 286 proposals. The ADVANCE proposal, entitled Read more
Trayanova Lab Publishes Precision Ablation Study in Nature Cardiovascular Research The Trayanova Lab at Johns Hopkins University is excited to announce the publication of our latest research in Nature Cardiovascular Research, “Assessing the arrhythmogenic propensity of fibrotic substrate using digital twins to inform a mechanisms-based atrial fibrillation ablation strategy,” (direct Read more
Trayanova Lab’s and JHMI Digital Twin Research Featured in Wall Street Journal On March 16th, the Wall Street Journal featured Dr. Trayanova and her lab’s work with JHMI on “digital twins” of people’s hearts– a method of creating a patient-specific model to study electrical problems and potentially guide therapy in a clinical environment. Read more
